Creative Biolabs

pPB Pep-LNP

Cat. No.: TDLD-0825-LD84

pPB Pep-LNP

pPB Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the pPB peptide, this LNP specifically binds to cell surface receptors, particularly relevant in the context of activated stromal cells like hepatic stellate cells, facilitating selective accumulation and interaction at the target site. Our LNP is prepared using Targeting Module and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of pPB Pep-LNP include research in fibrosis (especially liver fibrosis), cancer stroma targeting, and wound healing. Please note that this product is intended for research purposes only.

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SPECIFIC INQUIRY
Payload:
Modification:
Lipid Formulation:
Dye:
Concentration:
Quantity:
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For Research Use Only. Not for Diagnostic or Treatment Applications.
Payload Type mRNA
Payload Empty; EGFP mRNA; Firefly Luciferase mRNA; mCherry mRNA; GFP mRNA; OVA mRNA; EPO mRNA; Renilla Luciferase mRNA; Gaussia Luciferase mRNA; Beta-galactosidase mRNA; Cre mRNA; mOrange mRNA; tdTomato mRNA; EYFP mRNA; Others
Capping Cap 1
Modification Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine; Other
Module Type Peptide
Targeting Module pPB Peptide
Target Hepatic stellate cells
Lipid Formulation DLin-MC3-DMA; LP-01; ALC-0315; SM102; Other
Dye Unlabeled; DiR; DiD; DiO; DiI; Other
Application Targeted Delivery; Gene Therapy
Format Liquid
Concentration 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify)
Size 65-120 nm
PDI < 0.2
Zeta ± 20.0 mV
Encapsulate Efficiency >90%
Shipping Dry Ice
Storage Store at -80°C
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