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SP94 Pep-LNP

Cat. No.: TDLD-0825-LD86

SP94 Pep-LNP

SP94 Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the SP94 peptide, this LNP specifically recognizes and binds to particular receptors or antigens on the surface of hepatocellular carcinoma (HCC) cells, enabling precise targeting of liver cancer. Our LNP is prepared using DSPE-PEG-SP94 and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of SP94 Pep-LNP include developing targeted therapeutics and imaging probes for liver cancer, studying the biology of SP94 target antigens in HCC, and evaluating novel strategies for selectively delivering payloads to tumor cells for enhanced efficacy and reduced side effects. Please note that this product is intended for research purposes only.

SPECIFIC INQUIRY
Payload:
Modification:
Lipid Formulation:
Dye:
Concentration:
Quantity:
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For Research Use Only. Not for Diagnostic or Treatment Applications.
Payload Type mRNA
Payload Empty; EGFP mRNA; Firefly Luciferase mRNA; mCherry mRNA; GFP mRNA; OVA mRNA; EPO mRNA; Renilla Luciferase mRNA; Gaussia Luciferase mRNA; Beta-galactosidase mRNA; Cre mRNA; mOrange mRNA; tdTomato mRNA; EYFP mRNA
Capping Cap 1
Modification Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine
Module Type Peptide
Targeting Module SP94 Peptide
Target Hepatocellular carcinoma (HCC) cells
Lipid Formulation DLin-MC3-DMA; LP-01; ALC-0315; SM102
Dye Unlabeled; DiR; DiD; DiO; DiI
Application Control; Targeted Delivery; Gene Therapy
Concentration 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify)
Size 65-120 nm
PDI < 0.2
Zeta ± 20.0 mV
Encapsulate Efficiency >90%
Storage Store at 2-8°C
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