Biotinylated Human MSLN Protein (Glu 296-Gly 580) [Fc] (VAng-2560Lsx)
Biotinylated Human Mesothelin protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: AAH09272.1)
Datasheet
Specifications
Source
HEK293 cells
Target
MSLN
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
MSLN is a protein that in humans is encoded by MSLN gene. It is a 40 kDa protein that is expressed in mesothelial cells. It is over expressed in several human tumors, including mesothelioma, ovarian cancer, pancreatic adenocarcinoma and cholangiocarcinoma. The interaction between mesothelin and MUC16 (also known as CA125) may facilitate the implantation and peritoneal spread of tumors by cell adhesion. the region of MSLN has 64 amino acids at the N-terminus of cell surface mesothelin.
Alternative Names
MSLN, Mesothelin, MPF
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
