Biotinylated Human ROR1 Protein (Gln 30-Glu 403) [Fc] [avi] (VAng-2657Lsx)
Biotinylated Human ROR1 protein, human IgG1 Fc tag and Avi tag, was expressed in human 293 cells. (Uniprot ID: AAA60275.1)
Datasheet
Specifications
Source
HEK293 cells
Target
ROR1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Tris with Glycine, Arginine and NaCl, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
ROR1 (Receptor Tyrosine Kinase Like Orphan Receptor 1) modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia.
Alternative Names
ROR1, NTRKR1
Related Product
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