Biotinylated Human TFPI Protein (Asp 29-Lys 282) [His] (VAng-2767Lsx)
Biotinylated Human TFPI protein, His tag, primary amine labeling, was expressed in human 293 cells. (Uniprot ID: NP_006278.1)
Datasheet
Specifications
Source
HEK293 cells
Target
TFPI
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
TFPI (Tissue Factor Pathway Inhibitor) a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. Diseases associated with TFPI include Hemophilia and Thrombosis.
Alternative Names
TFPI, LACI, TFPI1, EPI, TFI
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
