Cancer Antigen CEA Antigen (Human Metastatic Liver of Colon Adenocarcinoma) (VAng-Wyb8646)
Carcinoembryonic Antigen, Antigen Grade, Cancer antigen from Human Metastatic Liver of Colon Adenocarcinoma, 7.8 mg/mL.
Datasheet
Specifications
Source
Human Metastatic Liver of Colon Adenocarcinoma.
Target
CEA
Type
Tumor Antigens
Applications
Immunoassays.
Formulation
20 mM Tris, pH 7.4 containing 100 mM Sodium Chloride.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C.
Antigen Information
Introduction
CEA is a member of the carcinoembryonic antigen family. It plays a role in cell adhesion, intracellular signaling and tumor progression. It mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules. The protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. Its gene is present in a CEA family on chromosome 19. Alternative splicing results in multiple transcript variants.
Alternative Names
CEACAM5
Related Product
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