CL413 (VAdv-Ly0026)

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VAdv-Ly0026

CL413, TLR2 & TLR7 agonist vaccine adjuvant.

Datasheet

Specifications

Type

PRRs Agonist

Formula

C₈₁H₁₄₅N₁₇O₁₂S

Molecular Weight

Specificity

TLR2 & TLR7 agonist

Product Form

White solid

Endotoxin

Lower than 5 EU/mg.

Storage

Store at -20°C.

Shelf Life

1 year.

Adjuvant Information

Introduction

CL413 is a hybrid molecule designed to simultaneously activate both the surface receptor TLR2 and the endosomal receptor TLR7. This compound features 8-hydroxyadenine, which serves as a ligand for TLR7, attached to the carboxylic acid terminus of Pam2CSK4, a ligand for TLR2.