CpG ODN 2006 (VAdv-Ly0034)
| CAT | Size | Price | Quantity | |
|---|---|---|---|---|
| VAdv-Ly0034 |
|
CpG ODN 2006, Class B (human), a synthetic immunostimulatory oligonucleotide, TLR9 agonist vaccine adjuvant.
Datasheet
Specifications
Type
CpG
Specificity
TLR9 agonist
Product Form
White solid
Endotoxin
Lower than 2 EU/mg.
Storage
Store at -20°C.
Shelf Life
1 year.
Adjuvant Information
Introduction
CpG ODN 2006 is a synthetic oligodeoxynucleotide designed to mimic bacterial DNA, specifically utilizing unmethylated cytosine-guanine (CpG) motifs to stimulate the immune system. As a Class B CpG ODN, it primarily targets Toll-like receptor 9 (TLR9), a key component of the innate immune response, particularly in B cells. This interaction triggers a cascade of signaling pathways, leading to the activation and proliferation of B cells and the production of pro-inflammatory cytokines.
Sequence
5'-tcgtcgttttgtcgttttgtcgtt-3' (24 mer)
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
