CpG ODN 2395 (VAdv-Ly0035)
| CAT | Size | Price | Quantity | |
|---|---|---|---|---|
| VAdv-Ly0035 |
|
CpG ODN 2395, class C (human / mouse), a synthetic immunostimulatory oligonucleotide, TLR9 agonist vaccine adjuvant.
Datasheet
Specifications
Type
CpG
Specificity
TLR9 agonist
Product Form
White solid
Endotoxin
Lower than 1 EU/mg.
Storage
Store at -20°C.
Shelf Life
1 year.
Adjuvant Information
Introduction
ODN 2395, a Class C Toll-like receptor 9 (TLR9) agonist effective in both human and murine models, elicits a dual immunostimulatory effect. It potently activates plasmacytoid dendritic cells (pDCs), driving high levels of interferon-alpha (IFN-α) production, while simultaneously stimulating B cells. This unique combination of properties, characteristic of Class C ODNs, bridges the functional attributes of both Class A and Class B ODNs. Consequently, ODN 2395 effectively triggers robust IFN-α release from pDCs and potent B cell activation, making it a valuable tool for research and potential therapeutic applications.
Sequence
5'-tcgtcgttttcggcgc:gcgccg-3' (22 mer)
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
