Cyclic Diadenylate Monophosphate (VAdv-Ly0021)
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| VAdv-Ly0021 |
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Cyclic diadenylate monophosphate, a STING agonist vaccine adjuvant.
Datasheet
Specifications
Type
PRRs Agonist
Formula
C20H22N10O12P2▪2Na
Molecular Weight
702.38
Specificity
Th1/Th2 response
Product Form
White solid
Percentage
≥ 95% by LC/MS
Endotoxin
Lower than 5 EU/mg.
Storage
Store at -20°C.
Shelf Life
1 year.
Adjuvant Information
Introduction
Cyclic diadenylate monophosphate (c-di-AMP), a bacterial intracellular signaling molecule, has shown promise as an adjuvant. When delivered mucosally, c-di-AMP induces a balanced Th1/Th2 immune response, along with a Th17 response, which is vital for combating intracellular pathogens. This adjuvant achieves its effect by attracting monocytes and granulocytes, and by promoting the maturation of dendritic cells.
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
