Human GFR alpha-1 Protein (Asp 25-Ser 424) [His] (VAng-1679Lsx)
Human GFR alpha-1 (GFRA1), His tag, is expressed in human 293 cells. (Uniprot ID: NP_665736.1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
GFRA1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
GFRA1 (GDNF Family Receptor Alpha 1) is a a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. Diseases associated with GFRA1 include Hirschsprung Disease 1 and Multiple Endocrine Neoplasia, Type Iia.
Alternative Names
GFRA1, GDNFRA, RETL1, TRNR1, GDNFR, GFR-ALPHA-1, RET1L
Related Product
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