Human GITR Ligand Protein (Gln 50-Ser 177) [His] (VAng-1684Lsx)
Human GITR Ligand (TNFRSF18), His tag, is expressed in human 293 cells. (Uniprot ID: AAH69319.1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
GITR Ligand
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
TNFRSF18 (TNF Receptor Superfamily Member 18) belongs to the TNF-receptor superfamily. The receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Alternative Names
TNFSF18, AITRL, TL6, hGITRL, GITR Ligand
Related Product
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