Human GITR Protein (Gln 26-Glu 161) [human IgG1 Fc Tag] (VAng-1688Lsx)
Human GITR (TNFRSF18), human IgG1 Fc Tag, is expressed in human 293 cells. (Uniprot ID: Q9Y5U5-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
GITR
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Tris with Glycine, Arginine and NaCl, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
TNFRSF18 (TNF Receptor Superfamily Member 18) belongs to the TNF-receptor superfamily. The receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Alternative Names
AITR, GITR, TNFRSF18, CD357
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
