Human Glutaredoxin 1 Protein (Met 1-Gln 106) [His] (VAng-1691Lsx)
Human Glutaredoxin 1 (GLRX1), His Tag, is expressed in E. coli. (Uniprot ID: NP_001112362)
Datasheet
Specifications
Source
E. coli.
Target
GLRX
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 150 mM NaCl, pH7.5 with 1 mM DTT.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
GLRX (Glutaredoxin) is a member of the glutaredoxin family. The protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease.
Alternative Names
GLRX, GRX, TTase-1, GLRX1, GRX1
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