Human IDI2 Protein (Ser 2-Val 227) [His] (VAng-1738Lsx)
Human IDI2, His tag, is expressed in E. coli. (Uniprot ID: AAH17778)
Applications
SDS-PAGE; WB; ELISA.
Formulation
150 mM NaCl, 50 mM Tris, pH 7.5 with 0.1 mM PMSF, 1 mM DTT.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
IDI2 (Isopentenyl-Diphosphate Delta Isomerase 2) catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis.
Alternative Names
IDI2, IPPI2, IPP isomerase 2
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