Human IL-1 beta Protein (Ala 117-Ser 269) (VAng-1751Lsx)

Human IL-1 beta (IL1B) is expressed in E. coli. (Uniprot ID: NP_000567)

Datasheet

Specifications

Source

E. coli.

Target

IL1B

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

IL1B is a cytokine protein that in humans is encoded by IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1beta precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature IL-1 beta. It is a member of the interleukin 1 family of cytokines. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.

Alternative Names

IL1B, IL-1BETA, IL1F2, IL-1β