Human IL-2 R alpha Protein (Glu 22-Cys 213) [Fc] (VAng-1800Lsx)

Human IL-2 R alpha, Fc tag, Human protein expressed in human 293 cells. (Uniprot ID: NP_000408)

Datasheet

Specifications

Source

HEK293 Cells.

Target

IL2RA

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Tris with Glycine, Arginine and NaCl, pH 7.5.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

IL2RA is a protein that in humans is encoded by IL2RA gene. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. Though IL2RA has been used as a marker to identify CD4+FoxP3+ regulatory T cells in mice, it has been found that a large proportion of resting memory T cells constitutively express IL2RA in humans. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor.

Alternative Names

IL2RA, CD25, p55, IL2-RA, IL-2-RA