Human IL-2 R alpha Protein (Glu 22-Cys 213) [His] [Avi] (VAng-1802Lsx)
Biotinylated Human IL-2 R alpha, His tag and Avi tag, Human protein expressed in human 293 cells. (Uniprot ID: P01589-1)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
IL2RA is a protein that in humans is encoded by IL2RA gene. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. Though IL2RA has been used as a marker to identify CD4+FoxP3+ regulatory T cells in mice, it has been found that a large proportion of resting memory T cells constitutively express IL2RA in humans. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor.
Alternative Names
IL2RA, CD25, p55, IL2-RA, IL-2-RA
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