Human IL-21 R Protein (Cys 20-Pro 236) [Fc] (VAng-1809Lsx)

Human IL-21 R, Fc tag, is expressed in human 293 cells. (Uniprot ID: AAH04348)

Specifications
Source
HEK293 Cells.
Target
IL21R
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 92% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
IL21R (Interleukin 21 Receptor) belongs to the type I cytokine receptors and is a cytokine receptor for interleukin 21 (IL21). It has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.
Alternative Names
IL21R, CD360, NILR
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