Human IL-23 alpha&IL-12 beta Heterodimer Protein (Arg 20-Pro 189 (IL23A)&Met 23-Ser 335 (IL12B)) (VAng-1813Lsx)

Human IL-23A&Mouse IL-12B Heterodimer protein is expressed in human 293 cells. (Uniprot ID: NP_057668 (IL23A)&NP_032378 (IL12B))

Datasheet

Specifications

Source

HEK293 Cells.

Target

IL12B

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

IL12B is a protein that in humans is encoded by IL12B gene. IL-12B is a common subunit of interleukin 12 and Interleukin 23. This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

Alternative Names

IL12B, CLMF, CLMF2, NKSF, NKSF2, p40; IL-23 alpha&IL-12 beta