Human IL5 Protein (Ile 20-Ser 134) [His] (VAng-1828Lsx)
Human IL5 protein, His tag, expressed in human 293 cells. (Uniprot ID: P05113-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
IL5
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
IL5 is an interleukin produced by type-2 T helper cells and mast cells. Through binding to the interleukin-5 receptor, interleukin 5 stimulates B cell growth and increases immunoglobulin secretion-primarily IgA. It is also a key mediator in eosinophil activation. It has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed. Given the high concordance of eosinophils and, in particular, allergic asthma pathology, it has been widely speculated that eosinophils have an important role in the pathology of this disease.
Alternative Names
IL-5, TRF, IL5, Interleukin-5
Related Product
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