Human ITGAE&ITGB7 Heterodimer Protein (Phe 19-Ser 1124 (ITGAE)&Glu 20-His 723 (ITGB7)) (VAng-1849Lsx)

Human ITGAE&ITGB7 Heterodimer protein, expressed in human 293 cells. (Uniprot ID: P38570-1 (ITGAE)&P26010-1 (ITGB7))

Datasheet

Specifications

Source

HEK293 Cells.

Target

ITGB7

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

ITGB7 (Integrin Subunit Beta 7) is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule.

Alternative Names

Integrin alpha E beta 7, ITGAE&ITGB7