Human Jagged 1 Protein (Gln 34-Asp 1067) (VAng-1857Lsx)
Human Jagged 1 (JAG1) protein, expressed in human 293 cells. (Uniprot ID: P78504-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
Jagged 1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
JAG1 (Jagged Canonical Notch Ligand 1) is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Alternative Names
CD339, JAG1, Jagged1, hJ1, JAGL1
Related Product
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