Human LAG3 Protein (Leu 23-Leu 450) [Llama IgG2b Fc tag] (VAng-1872Lsx)
Human LAG3 protein, Llama IgG2b Fc tag, expressed in human 293 cells. (Uniprot ID: P18627-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
LAG3
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Tris with Glycine, Arginine and NaCl, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
LAG3 is a protein which in humans is encoded by LAG3 gene. It is a cell surface molecule with diverse biologic effects on T cell function. It is an immune checkpoint receptor and as such is the target of various drug development programs by pharmaceutical companies seeking to develop new treatments for cancer and autoimmune disorders. In soluble form it is also being developed as a cancer drug in its own right. The LAG3 protein, which belongs to immunoglobulin (Ig) superfamily, comprises a 503-amino acid type I transmembrane protein with four extracellular Ig-like domains, designated D1 to D4.
Alternative Names
LAG3, CD223, FDC
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
