Human Mutant IRF-3 Plasmid Adjuvant (VCar-Ly033)
Express a human mutant interferon regulatory factor 3 (IRF-3) gene.
Source
Human super-activated IRF-3 gene
Type
Dendrimers&Cyclopeptides
Applications
For DNA vaccine delivery.
Introduction
The mIRF-3 plasmid encodes a mutant interferon regulatory factor 3 (IRF-3) gene. The IRF-3 gene directly activates the expression of interferon (IFN-α/β) and its downstream antiviral and anti-tumor genes by delivering the interferon regulatory factor IRF-3 to target cells. This process enhances the innate immune response and bridges to adaptive immunity. Delivery vectors, including viral (adenovirus) and non-viral forms (lipid nanoparticles/mRNA-LNP), can be modified to improve specificity for applications in antiviral therapy, tumor immunotherapy, and vaccine adjuvant development.
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.