Human NKG2D Protein (Ile 73-Val 216) [His] (VAng-2609Lsx)
Human NKG2D (CD314) protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P26718-1)
Datasheet
Specifications
Source
HEK293 cells
Target
NKG2D
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH 7.5.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
KLRK1 (Killer Cell Lectin Like Receptor K1) is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers.
Alternative Names
NKG2D, CD314, KLRK1, NK cell receptor D
Related Product
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