Human NKG2D Protein (Ile 73-Val 216) [His] (HPLC-verified) (VAng-2607Lsx)
Human NKG2D (CD314) protein, His tag, HPLC-verified, was expressed in human 293 cells. (Uniprot ID: P26718-1)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
KLRK1 (Killer Cell Lectin Like Receptor K1) is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers.
Alternative Names
NKG2D, CD314, KLRK1, NK cell receptor D
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