Human Serpin H1 Protein (Ala 19-Leu 418) [His] (VAng-2696Lsx)
Human Serpin H1 protein, His tag, was expressed in human 293 cells. (Uniprot ID: NP_001226)
Datasheet
Specifications
Source
HEK293 cells
Target
Serpin H1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
SERPINH1 (Serpin Family H Member 1) is a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Diseases associated with SERPINH1 include Osteogenesis Imperfecta, Type X and Preterm Premature Rupture Of The Membranes.
Alternative Names
SERPINH1, Serpin H1, HSP47, CBP1, CBP2, SERPINH2, PIG14, AsTP3, Colligin, OI10, PPROM, RA-A47, gp46
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