Human Syndecan-1 Protein (Gln 23-Gly 254) [His] (VAng-2760Lsx)
Human Syndecan-1 protein, His tag, was expressed in human 293 cells. (Uniprot ID: AAH08765)
Datasheet
Specifications
Source
HEK293 cells
Target
SDC1
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
SDC1 (Syndecan 1) is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. Diseases associated with SDC1 include Mucinous Bronchioloalveolar Adenocarcinoma and Granulomatous Endometritis.
Alternative Names
SDC1, Syndecan-1, CD138, SYND1, SDC
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