Human Tau-441 Protein (Met 1-Leu 441) [His] (VAng-2763Lsx)

Human Tau-441 protein, His tag, was expressed in E. coli. (Uniprot ID: P10636-8)

Specifications
Source
E. coli
Target
MAPT
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH 7.5.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
MAPT (Microtubule Associated Protein Tau) is the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Alternative Names
DDPAC, FTDP-17, MAPT, MSTD, MTBT1, Tau, PHF-tau, TAU

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