Human TNFSF14 Protein (Asp 74-Val 240) [human IgG1 Fc tag] (VAng-1913Lsx)

Human TNFSF14 protein, human IgG1 Fc tag, expressed in human 293 cells. (Uniprot ID: O43557-1)

Datasheet

Specifications

Source

HEK293 Cells.

Target

TNFSF14

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Tris with Glycine, Arginine and NaCl, pH 7.5.

Purity

> 85% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

TNFSF14 (TNF Superfamily Member 14) is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte.

Alternative Names

CD258 antigen, CD258, HVEM-L, LIGHT, LTg, TNFSF14, TR2, HVEML