Mouse IL-17A Protein (Ala 26-Ala 158) [His] (VAng-1934Lsx)
Mouse IL-17A (CTLA-8), His tag, is expressed in human 293 cells. (Uniprot ID: Q62386-1)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
IL17A (Interleukin 17A) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Alternative Names
IL-17A, Interleukin-17A, CTLA-8, IL-17
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