Mouse Jagged 1 Protein (Gln 34-Asp 1067) (VAng-1941Lsx)
Mouse Jagged 1 (JAG1) protein, expressed in human 293 cells. (Uniprot ID: Q9QXX0-1)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
JAG1 (Jagged Canonical Notch Ligand 1) is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Alternative Names
CD339, JAG1, Jagged1, hJ1, JAGL1
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