Mouse RENIN Protein (Leu 22-Arg 402) [His] (VAng-2651Lsx)

Mouse RENIN protein, His tag, was expressed in human 293 cells. (Uniprot ID: NP_112469.1)

Specifications
Source
HEK293 cells
Target
REN
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
REN (Renin) catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance.
Alternative Names
REN, FLJ10761, Renin, angiotensinogenase
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