Mouse SIRP alpha Protein (Lys 32-Asn 373) [human IgG1 Fc tag] (VAng-2729Lsx)
Mouse SIRP alpha protein, human IgG1 Fc tag, was expressed in human 293 cells. (Uniprot ID: P97797.1)
Datasheet
Specifications
Source
HEK293 cells
Target
SIRPA
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS with Arginine, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
SIRPA (Signal Regulatory Protein Alpha) is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors.
Alternative Names
SHPS1, SIRPA, CD172A, BIT, MFR, MYD1, P84, PTPNS1
Related Product
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