ODN 1585-Murine TLR9 Agonist Controls and Conjugates (Antigen Grade) (VAdv-Ly0014)
ODN 1585, murine TLR9 agonist, Oligodeoxy Nucleotide vaccine adjuvant.
Product Form
White powder
Endotoxin
Lower than 1 EU/mg
Introduction
ODN 1585 is a Type A murine TLR9 agonist whose mechanism of action preferably involves indirect activation of the natural killer cells, induced regression of the MHC class I-deficient tumors TC1/A9 but not of the MHC class Iproficient tumors TC-1.The synthetic CpG ODN have a potential for the therapy of both MHC class I-proficient and -deficient tumors and thus could be also used against tumors that tend to downregulate their MHC class I expression.
Sequence
5'-ggGGTCAACGTTGAgggggg-3' (20 mer)
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.