Recombinant 2B4 / CD244 / SLAMF4 Protein (Cys 22-Arg 221 ) [His] (VAng-0690Lsx)
Human 2B4 Protein, His tag, was expressed in HEK 293 cells, with a molecular weight of 23.1 kDa. (Uniprot ID: NP_057466)
Datasheet
Specifications
Source
HEK293 Cells.
Target
2B4
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
2B4 is a human protein encoded by 2B4 gene. This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) and some T cells, mediating non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. CD244 can also be expressed on non-lymphocytes such as eosinophils, mast cells and dendritic cells.
Alternative Names
CD244; NAIL; NKR2B4; Nmrk; SLAMF4; CD244 molecule; 2B4; SLAMF4; NKR2B4; NAIL; h2B4
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
