Recombinant 2B4 Protein (Met1-Arg221) [His] (VAng-Cr3853)

Recombinant 2B4 Protein (Met1-Arg221) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 45-50 kDa. (Uniprot ID: Q9BZW8)

Datasheet

Specifications

Source

Mammalian cells

Target

2B4

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Protein lyophilized in sterile PBS/Protein store in sterile PBS.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20 °C to -80 °C.

Antigen Information

Introduction

2B4 is a human protein encoded by 2B4 gene. This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) and some T cells, mediating non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. CD244 can also be expressed on non-lymphocytes such as eosinophils, mast cells and dendritic cells.

Alternative Names

CD244; NAIL; NKR2B4; Nmrk; SLAMF4; CD244 molecule