Recombinant 4-1BB Ligand / TNFSF9 Protein (aa 52-254) (VAng-2789Lsx)
Recombinant 4-1BB ligand was expressed in E. coli. (Uniprot ID: P41273)
Datasheet
Specifications
Source
E. coli
Target
4-1BBL
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
4-1BBL is found on APCs (antigen presenting cells) and binds to 4-1BB. Therapies utilizing the 4-1BB:4-1BBL signaling pathway have been shown to have antitumor effects in a number of model systems. It is a membrane bound member of the TNF superfamily that is expressed on activated B-cells; macrophage; and dendritic cells. The ligand is specific for the 4-1BB receptor and may play a role in inducing the proliferation of activated peripheral blood T-cells.
Alternative Names
4-1BB ligand; TNFSF9; CD137L
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
