Recombinant ADAM8 Protein (Ile 17-Pro 497) [His] (VAng-0710Lsx)

Human ADAM8, His tag, is expressed in HEK 293 cells. (Uniprot ID: AAI15405.1)

Datasheet

Specifications

Source

HEK293 Cells.

Target

ADAM8

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

50 mM Tris, 150 mM NaCl, 20 mM CaCl₂, pH 7.5.

Purity

> 85% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

ADAM8 (ADAM Metallopeptidase Domain 8) is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.

Alternative Names

ADAM8, MS2, CD156a