Recombinant APP Protein (Met1-Leu669) [His] (VAng-Cr3798)
Recombinant APP Protein (Met1-Leu669) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 98.59 kDa. (Uniprot ID: P05067)
Datasheet
Specifications
Source
Mammalian cells
Target
APP
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
APP is lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. unctions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. It is involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP.
Alternative Names
A4; AD1
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
