Recombinant B7-H5 Protein (Phe 33-Ala 194) [His] (VAng-1100Lsx)
Human B7-H5, His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH20568)
Datasheet
Specifications
Source
HEK293 Cells.
Target
B7-H5
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
B7-H5, also known as V-domain Ig suppressor of T cell activation (VISTA) is a type I transmembrane protein that functions as an immune checkpoint. VISTA is produced at high levels in tumor-infiltrating lymphocytes, such as myeloid-derived suppressor cells and regulatory T cells, and its blockade with an antibody results in delayed tumor growth in mouse models of melanoma and squamous cell carcinoma.
Alternative Names
B7-H5, SISP1, Gi24, VISTA
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
