Recombinant Canine SDF-1 Protein (aa 22-93) (VAng-Cr3949)
Recombinant Canine SDF-1 Protein (Lys22-Met93) was expressed in E. coli, with a molecular weight of 8.6 kDa. (Accession ID: NP_001121569.1)
Formulation
Lyophilized from sterile PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
SDF-1 is a chemokine protein in humans. It is ubiquitously expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The chemokines are characterized by the presence of 4 conserved cysteines that form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, the cysteine residues are adjacent to each other. In the CXC subfamily, they are separated by an intervening amino acid. During embryogenesis, it directs the migration of hematopoietic cells from fetal liver to bone marrow and the formation of large blood vessels. It plays an important role in angiogenesis by recruiting endothelial progenitor cells (EPCs) from the bone marrow through a CXCR4 dependent mechanism
Alternative Names
CXCL12; IRH; PBSF; SCYB12; SDF1; TLSF
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