Recombinant Carbonic Anhydrase III Protein (Met 1-Lys 260) [His] (VAng-1159Lsx)

Human Carbonic Anhydrase III (CA3), His tag, is expressed in E. coli. (Uniprot ID: NP_005172)

Specifications
Source
E. coli
Target
Carbonic Anhydrase III
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 150 mM NaCl, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal.
Alternative Names
CA3, Carbonic anhydrase 3
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