Recombinant Cathepsin D Protein (Ser 19-Leu 412) [His] (VAng-1168Lsx)

Human Cathepsin D (CTSD), His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001900)

Datasheet

Specifications

Source

HEK293 Cells.

Target

Cathepsin D

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

50 mM MES, 100 mM NaCl, pH 6.5.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

CTSD (Cathepsin D) is a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Alternative Names

CTSD, Cathepsin D, CPSD, CLN10