Recombinant CD19 Protein (Met1-Trp290) [His] (VAng-Cr3780)
Recombinant CD19 Protein (Met1-Trp290) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 45 kDa. (Uniprot ID: P15391)
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Introduction
CD19 is a transmembrane protein that in humans is encoded by CD19 gene. CD19 is expressed in all B lineage cells, except for plasma cells, and in follicular dendritic cells. CD19 plays two major roles in human B cells. It acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane and it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.
Alternative Names
B4; CVID3; CD19 molecule
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