Human CD19 Protein (Pro 20-Lys 291) [Fc] (VAng-1207Lsx)
Human CD19, human IgG1 Tag, is expressed in HEK 293 cells. (Uniprot ID: AAH06338)
Applications
SDS-PAGE; WB; ELISA.
Formulation
Tris with Glycine, Arginine and NaCl, pH 7.5.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
CD19 is a transmembrane protein that in humans is encoded by CD19 gene. CD19 is expressed in all B lineage cells, except for plasma cells, and in follicular dendritic cells. CD19 plays two major roles in human B cells. It acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane and it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.
Alternative Names
CD19, B4, CVID3, MGC12802
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