Recombinant CD19 Protein (Pro 20-Lys 291) [His] (VAng-1209Lsx)

Human CD19, His Tag, is expressed in HEK 293 cells. (Uniprot ID: P15391-1)

Datasheet

Specifications

Source

HEK293 Cells.

Target

CD19

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Tris with Glycine, Arginine and NaCl, pH 7.5.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

CD19 is a transmembrane protein that in humans is encoded by CD19 gene. CD19 is expressed in all B lineage cells, except for plasma cells, and in follicular dendritic cells. CD19 plays two major roles in human B cells. It acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane and it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.

Alternative Names

CD19, B4, CVID3, MGC12802