Recombinant CD28 Protein (Met1-Pro152) [Fc] (VAng-Cr3826)

Recombinant CD28 Protein (Met1-Pro152) fused with a Fc tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 42.63 kDa. (Uniprot ID: P10747)

Datasheet

Specifications

Source

Mammalian cells

Target

CD28

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Protein lyophilized in sterile PBS/Protein store in sterile PBS.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20 °C to -80 °C.

Antigen Information

Introduction

CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive (expression is independent of environmental factors).

Alternative Names

Tp44; CD28 molecule