Recombinant CD3 epsilon Protein (Gln 22-Asp 117) [His] [Fc] (VAng-1255Lsx)
Cynomolgus CD3 epsilon, His tag and Fc tag, is expressed in HEK 293 cells. (Uniprot ID: Q95LI5)
Datasheet
Specifications
Source
HEK293 Cells.
Target
CD3E
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD3E (CD3 epsilon) is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Alternative Names
FLJ18683, T3E, TCRE, CD3E, CD3-epsilon
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
